Antifungal and Antioxidant Activities of Lipophilic Compounds from Swietenia mahagoni (l.) Jacq. Leaves

Masendra Masendra, Brandon Aristo Verick Purba, Rizki Arisandi, Ganis Lukmandaru

Abstract


The investigation on the n-hexane lipophilic extractives of Swietenia mahagoni, alongside the antifungal and antioxidant properties was conducted. The leaf sample was collected from 2- and 3-years-old trees in Perhutani enterprise of Temanggung, Central Java, Indonesia. In addition, the antifungal activity was tested using the white-rot of Phanerochaete chrysosporium, while the antioxidant property involved the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The results show antifungal of 28.6% and 37.5% growth inhibition in 2- and 3 -years-old leaf, respectively, while 21.7% and 25.4% antioxidant activity were also recorded. Furthermore, the GC-MS results showed the domination of S. mahagoni leaf by fatty acids and hydo-carbons, while the terpenoids and steroids were in minor quantities. These components possibly exhibit growth inhibitory and antioxidant effects against P. chrysosporium and DPPH radicals, respectively.

Keywords


S. mahagoni; leaves; lipophilics; antifungal; antioxidant; hydrocarbons

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References


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DOI: https://doi.org/10.51850/wrj.2015.6.2.62-68

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